TLR3 anticorps

N° du produit ABIN920707

Cet anticorps Souris Monoclonal détecte spécifiquement TLR3 dans WB et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour TLR3 anticorps (ABIN920707)

Antigène: TLR3 (Toll-Like Receptor 3 (TLR3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TLR3 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-TLR3 anticorps

Specificité: Reacts with TLR3.

Stérilité: 0.2 μm filtered

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: (intracellular) Use at a 1:10 dilution. Western blot: Use at a 1:10 dilution.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 1 mL of 0.2 µm sterile filtered antibody solution at 100 µg/mL in PBS containing 0.1% protein stabilizer.

Stock: 4 °C

Détails sur TLR3

Antigène: TLR3 (Toll-Like Receptor 3 (TLR3))

Autre désignation: TLR3

Sujet: Toll-like receptors (TLR) are highly conserved throughout evolution and have been implicated in the innate defence to many pathogens. In Drosophila toll is required for the anti-fungal response, while the related 18-wheeler is involved in antibacterial defences. In mammals, TLR identified as type I transmembrane signalling receptors with pattern recognition capabilies, have been implicated in the innate host defence to pathogens. As investigated so far all functional characterized TLR signal via the TLR/IL-1 receptor (IL-1R) pathway where recruitment of MyD88 seems to be essential. Viral replication within infected cells results in generation of dsRNA which can stimulate immune cells. Recent data show that TLR3 acts as a receptor involved in the recognition of dsRNA, indicating a role for TLR3 in viral recognition and innate defence.

Pathways: Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades